Effects of Mild Stresses Applied in Adults on Aging and Longevity

Eric Le Bourg (1)

1 CRCA - Centre de Recherches sur la Cognition Animale - UMR5169

It is now known that some mild stresses can have positive effects on longevity, aging, and resistance to severe stresses in several species, and particularly in Drosophila melanogaster flies. This chapter describes the effects of some mild stresses (heat, cold hypergravity, oxidative stress, fasting, and so on) in flies and the possible mechanisms of these mild stresses (antioxidant enzymes, heat shock proteins, NF-κB).

Mots clés: Drosophila melanogaster — Mild stress — Hormesis — Aging — Longevity — Severe stresses — Heat shock proteins — Antioxidant enzymes — NF-κB

Domaines: Gériatrie et gérontologie

Eric Le Bourg. Effects of Mild Stresses Applied in Adults on Aging and Longevity. Vaiserman, Alexander, Moskalev, Alexey, Pasyukova, Elena (Eds.). Life Extension Lessons from Drosophila, Springer International Publishing, pp.301-320, 2015, 978-3-319-18325-1. ⟨10.1007/978-3-319-18326-8⟩. ⟨hal-01163572⟩