Realistic Simulation of Electric Potential Distributions of Different Stimulation Modes in an Implanted Cochlea

Kai Dang (1, 2) , Clair Vandersteen (3) , Nicolas Guevara (3) , Maureen Clerc (1) , Dan Gnansia (2)

1 ATHENA - Computational Imaging of the Central Nervous System
2 Oticon Medical / Neurelec
3 Institut Universitaire de la Face et du Cou [Nice]

Simulation of the intracochlear potentials is an important approach to study the activation of auditory nerve fibers under electrical stimulations. However, it is still unclear to which extent the simulation results are affected by precision in reproducing the exact cochlear geometry. In this study, we address to this question by comparing the actual electric potential measured from implanted human specimen with the simulation outputs from two different parametric 3D cochlear models. One of the model is created from the default values[1] while the other is adapted to the micro-CT scan data of the implanted cochlea.

Domaines: Bio-informatique [q-bio.QM]

Kai Dang, Clair Vandersteen, Nicolas Guevara, Maureen Clerc, Dan Gnansia. Realistic Simulation of Electric Potential Distributions of Different Stimulation Modes in an Implanted Cochlea. Association of Research in Otolaryngology 38th MidWinter Meeting, Feb 2015, Baltimore, United States. ⟨hal-01128098⟩