Biophysical modelling of the intrinsic mechanisms of the autonomous starbust cells during stage II retinal waves

Dora Karvouniari (1) , Lionel Gil (2) , Olivier Marre (3) , Serge Picaud (3) , Bruno Cessac (1)

1 BIOVISION - Biologically plausible Integrative mOdels of the Visual system : towards synergIstic Solutions for visually-Impaired people and artificial visiON
2 INLN - Institut Non Linéaire de Nice Sophia-Antipolis
3 Institut de la Vision

Retinal waves are spontaneous bursting activity propagating in the developping retina until vision is functional. In this work we propose a biophysical modelling of the mechanism that generates the spontaneous intrinsic cell-autonomous rhythmic bursting in Starbust Amacrine Cells (SACs), observed experimentally in [1] which is directly linked with the emergence of stage II retinal waves. We analyze this system from the dynamical system and bifurcation theory perspective.

Domaines: Science non linéaire [physics]; Biophysique [physics.bio-ph]; Neurosciences [q-bio.NC]

Dora Karvouniari, Lionel Gil, Olivier Marre, Serge Picaud, Bruno Cessac. Biophysical modelling of the intrinsic mechanisms of the autonomous starbust cells during stage II retinal waves. Modelling the early visual system - Workshop, Jan 2016, Paris, France. ⟨hal-01256477⟩