A Computational Model of Dual Competition between the Basal Ganglia and the Cortex

Meropi Topalidou (1) , Daisuke Kase (2) , Thomas Boraud (2) , Nicolas P. Rougier (1)

1 Mnemosyne - Mnemonic Synergy
2 IMN - Institut des Maladies Neurodégénératives [Bordeaux]

We propose a model that includes interactions between the cortex, the basal ganglia and the thalamus based on a dual competition. We hypothesize that the striatum, the subthalamic nucleus, the internal pallidum (GPi), the thalamus, and the cortex are involved in closed feedback loops through the hyperdirect and direct pathways. These loops support a competition process that results in the ability of basal ganglia to make a cognitive decision followed by a motor one. Considering lateral cortical interactions, another competition takes place inside the cortex allowing the latter to make a cognitive and a motor decision. We show how this dual competition endows the model with two regimes. One is driven by reinforcement learning, the other by Hebbian learning. The final decision is made according to a combination of these two mechanisms with a gradual transfer from the former to the latter. We confirmed these theoretical results on primates (Macaca mulata) using a novel paradigm predicted by the model.

Mots clés: Short-range Excitation; Competition; Action Selection; Cortex; Basal Ganglia; Thalamus; Reinforcement Learning; Hebbian Learning; Covert Learning; Stimulus-Response; Action-Outcome; Decision making

Domaines: Neurosciences; Neurosciences [q-bio.NC]; Modélisation et simulation

Meropi Topalidou, Daisuke Kase, Thomas Boraud, Nicolas P. Rougier. A Computational Model of Dual Competition between the Basal Ganglia and the Cortex. eNeuro, 2018, pp.ENEURO.0339--17.2018. ⟨hal-01925643⟩