Evidence that the activation of substrates used for the condensation leading to the synthesis of Mycolic acids required the acyl-AMP ligase FadD32 and an AccD4-containing Acyl-CoA carboxylase

D. Portevin (1) , De Souza-d'Auria C. , H. Montrozier (1) , Houssin Ch. , A. Stella (1) , Lanéelle Ma. (1) , F. Bardou (1) , C. Guilhot (1) , M. Daffé (1)

1 IPBS - Institut de pharmacologie et de biologie structurale

Domaines: Microbiologie et Parasitologie; Biochimie, Biologie Moléculaire

D. Portevin, De Souza-d'Auria C., H. Montrozier, Houssin Ch., A. Stella, et al.. Evidence that the activation of substrates used for the condensation leading to the synthesis of Mycolic acids required the acyl-AMP ligase FadD32 and an AccD4-containing Acyl-CoA carboxylase. Journal of Biological Chemistry, 2005, 280 (10), pp.8862-8874. ⟨hal-00078690⟩