The MEDICALIP Project: Toward the screening of the cytomegalovirus

B. Wacogne (1) , J.-S. Guerrini (2) , T. Mangeat (1) , H. Benalia (1) , C. Pieralli (1) , A. Rouleau (1) , W. Boireau (1) , A. Coaquette (3) , G. Herbein (3) , C. Davrinche (4) , L. Pazart (2)

1 FEMTO-ST - Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174)
2 INSERM-CIT 808
3 API - Agents pathogènes et inflammation - UFC (EA 4266)
4 UT3 - Université Toulouse III - Paul Sabatier

ince rubella vaccine was established, cytomegalovirus infection has become the most frequent cause of congenital infections. The French Health Authority is urging a diagnosis at birth for newborns. Since no screening device is commercially available, a consortium has been established to set-up an original device. The project has been funded by the French National Research Agency. The device consists of a disposable cartridge containing the biological sample and the reactive liquids required for immuno-fluorescencence detection on a functionalized surface. It also consists of a mobile reader used to drive the fluids onto the biosensor and to ensure the optical measurement. Positive and negative samples can be discriminated with a fluorescence intensity ratio of 3.

Mots clés: Cytomegalovirus; Immuno-fluorescence; Mobile medical device; Screening

Domaines: Optique / photonique

B. Wacogne, J.-S. Guerrini, T. Mangeat, H. Benalia, C. Pieralli, et al.. The MEDICALIP Project: Toward the screening of the cytomegalovirus. Innovation and Research in BioMedical engineering, 2011, 32 (2), pp.66-68. ⟨10.1016/j.irbm.2011.01.022⟩. ⟨hal-00583473⟩