Biomimetic nanocrystalline apatite coatings synthesized by Matrix Assisted Pulsed Laser Evaporation for medical applications

Anita Ioana Visan (1) , David Grossin (2) , Nicolaie Stefan (1) , Liviu Duta (1) , Floralice Marimona Miroiu (1) , George E. Stan (3) , Mihai Sopronyi (1) , Catalin Luculescu (1) , Michèle Freche (2) , Olivier Marsan (2) , Cédric Charvillat (2) , Sorin Ciuca (4) , Ion N. Mihailescu (1)

1 INFLPR - National Institute for Lasers, Plasma, and Radiation Physics [Magurele-Ilfov]
2 CIRIMAT - Centre interuniversitaire de recherche et d'ingenierie des matériaux
3 National Institute for Materials Physics - NIMP (ROMANIA)
4 UPB - University Politehnica of Bucharest [Romania]

We report the deposition by Matrix Assisted Pulsed Laser Evaporation (MAPLE) technique of biomimeticnanocrystalline apatite coatings on titanium substrates, with potential application in tissue engineering.The targets were prepared from metastable, nanometric, poorly crystalline apatite powders, analogousto mineral bone, synthesized through a biomimetic approach by double decomposition process. For thedeposition of thin films, a KrF* excimer laser source was used (λ = 248 nm, τFWHM ≤ 25 ns). The analy-ses revealed the existence, in synthesized powders, of labile non-apatitic mineral ions, associated withthe formation of a hydrated layer at the surface of the nanocrystals. The thin film analyses showedthat the structural and chemical nature of the nanocrystalline apatite was prevalently preserved. Theperpetuation of the non-apatitic environments was also observed. The study indicated that MAPLE isa suitable technique for the congruent transfer of a delicate material, such as the biomimetic hydratednanohydroxyapatite.

Mots clés: Biomimetic hydrated bioapatites; Thin films; Matrix Assisted Pulsed Laser Evaporation- MAPLE; Coated implants

Domaines: Matériaux

Anita Ioana Visan, David Grossin, Nicolaie Stefan, Liviu Duta, Floralice Marimona Miroiu, et al.. Biomimetic nanocrystalline apatite coatings synthesized by Matrix Assisted Pulsed Laser Evaporation for medical applications. Masterials Science and Engineering : B, 2014, vol. 181, pp. 56-63. ⟨10.1016/j.mseb.2013.11.007⟩. ⟨hal-01073843⟩