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MULTILEVEL (3D) MICROFLUIDIC TECHNOLOGY FOR AN INNOVATIVE MAGNETIC CELL SEPARATION PLATFORM

Abstract : We demonstrate a new concept of devices, which by combining 3D fluid engineering and localized mag-netic actuation enables the full integration of a cell tagging and magnetic separation device. We used a low cost, commercially available dry film (EMS Inc, Ohio, USA) that fits microfluidic requirements and gives the possibility to build easily 3D microfluidic structures. The labelling of blood monocytes with su-perparamagnetic particles was performed "up stream" with the aim of a microparticles 3D micromixer while cell separation was achieved "downstream" through continuous vertical separation over integrated micro-coils.
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https://hal.archives-ouvertes.fr/hal-01086517
Contributor : Marc Fouet <>
Submitted on : Monday, November 24, 2014 - 2:08:41 PM
Last modification on : Thursday, February 20, 2020 - 6:16:02 PM
Long-term archiving on: : Wednesday, February 25, 2015 - 10:50:37 AM

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  • HAL Id : hal-01086517, version 1

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Marc Fouet, Sébastien Cargou, Rémi Courson, Marie-Charline Blatché, A Montrose, et al.. MULTILEVEL (3D) MICROFLUIDIC TECHNOLOGY FOR AN INNOVATIVE MAGNETIC CELL SEPARATION PLATFORM. 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Oct 2014, San Antonio, United States. pp.440-442. ⟨hal-01086517⟩

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