Acute dyspnoea and single tracheal localisation of mantle cell lymphoma.

Jean-Christophe Ianotto (1) , Adrian Tempescul (1, 2) , Jean-Richard Eveillard (3) , Norbert André (4) , Frédéric Morel (5) , Isabelle Quintin-Roué (6) , Christian Berthou (2, 7)

1 Service Hématologie
2 EA2216 - Immunologie et Pathologie
3 CHU-Brest-Hemato - CHRU Brest - Service d'Hématologie
4 IRAP - Institut de recherche en astrophysique et planétologie
5 LAMPA - Laboratoire Angevin de Mécanique, Procédés et InnovAtion
6 CHU - AnaPath - CHRU Brest - Laboratoire d'Anatomo-Pathologie
7 UEB - Université européenne de Bretagne - European University of Brittany

Mantle cell lymphoma is a lymphoid entity characterized by adenopathy, blood and bone marrow involment which only recurrent mucosal localisation is the lymphomatoid polyposis. Few other mucosal infiltrations have been already reported. We report here the first case of a unique tracheal localisation of mantle cell lymphoma at presentation of the disease. The presence of classical t(11;14)(q13;q32) confirmed the diagnosis of mantle cell lymphoma by eliminating MALT or cancer localisation. This case illustrates the necessity to ensure the diagnosis of mucosal lymphoma versus MCL since these diseases need different treatment regimens and prognoses.

Domaines: Immunologie

Jean-Christophe Ianotto, Adrian Tempescul, Jean-Richard Eveillard, Norbert André, Frédéric Morel, et al.. Acute dyspnoea and single tracheal localisation of mantle cell lymphoma.. Journal of Hematology and Oncology, 2009, 3, pp.34. ⟨hal-01150977⟩