F. A. Edwards, A. Konnerth, B. Sakmann, and T. Takahashi, A thin slice preparation for patch clamp recordings from neurones of the mammalian central nervous system, Pfl???gers Archiv European Journal of Physiology, vol.31, issue.5, pp.414-600, 1989.
DOI : 10.1007/BF00580998

O. Marre, A. Dario, N. Deshmukh, K. Sadeghi, F. Soo et al., Mapping a Complete Neural Population in the Retina, Journal of Neuroscience, vol.32, issue.43, pp.32-14859, 2012.
DOI : 10.1523/JNEUROSCI.0723-12.2012

M. E. Spira and A. Hai, Multi-electrode array technologies for neuroscience and cardiology, Nature Nanotechnology, vol.2010, issue.2, pp.83-94, 2013.
DOI : 10.1103/PhysRevLett.96.228102

F. O. Morin, Y. Takamura, and E. Tamiya, Investigating neuronal activity with planar microelectrode arrays: achievements and new perspectives, Journal of Bioscience and Bioengineering, vol.100, issue.2, pp.131-143, 2005.
DOI : 10.1263/jbb.100.131

C. Xie, Z. Lin, L. Hanson, Y. Cui, B. Cui et al., Intracellular recording of action potentials by nanopillar electroporation, Nature Nanotechnology, vol.88, issue.3, pp.185-190, 2012.
DOI : 10.1038/nnano.2012.8

Y. Nam, J. Chang, D. Khatami, G. J. Brewer, and B. C. Wheeler, Gold-Coated Microelectrode Array With Thiol Linked Self-Assembled Monolayers for Engineering Neuronal Cultures, IEEE Transactions on Biomedical Engineering, vol.51, issue.1, pp.151-109, 2004.
DOI : 10.1109/TBME.2003.820336

D. Ghezzi, M. R. Antognazza, M. Dal-maschio, E. Lanzarini, F. Benfenati et al., A hybrid bioorganic interface for neuronal photoactivation, Nature Communications, vol.1, pp.166-167, 2011.
DOI : 10.1038/ncomms1164

G. Buzsáki, C. A. Anastassiou, and C. Koch, The origin of extracellular fields and currents ??? EEG, ECoG, LFP and spikes, Nature Reviews Neuroscience, vol.9, issue.6, pp.13-407, 2012.
DOI : 10.1038/nrn3241

. Biscarini, Organic ultra-thin film transistors with a liquid gate for extracellular stimulation and 11

. Martinoia, Active pixel sensor array for high spatio-temporal resolution electrophysiological recordings from single cell to large scale neuronal networks, pp.2644-2651, 2009.

A. Hierlemann, U. Frey, S. Hafizovic, and F. Heer, Growing Cells Atop Microelectronic Chips: Interfacing Electrogenic Cells In Vitro With CMOS-Based Microelectrode Arrays, Proceedings of the IEEE, pp.99-252, 2011.
DOI : 10.1109/JPROC.2010.2066532

O. Wiener, H. P. Paul, P. Neves, and . Ruther, Fabrication technology for silicon-based microprobe arrays used in acute and sub-chronic neural recording, Journal of Micromechanics and Microengineering, pp.19-20, 2009.

J. Pine, Recording action potentials from cultured neurons with extracellular microcircuit electrodes, Journal of Neuroscience Methods, vol.2, issue.1, pp.19-31, 1980.
DOI : 10.1016/0165-0270(80)90042-4

G. W. Gross, A. N. Williams, and J. H. Luca, Recording of spontaneous activity with photoetched microelectrode surfaces from mouse spinal neurons in culture, Journal of Neuroscience Methods, vol.5, issue.1-2, pp.13-22, 1982.
DOI : 10.1016/0165-0270(82)90046-2

P. Fromherz, Electrical Interfacing of Nerve Cells and Semiconductor Chips, ChemPhysChem, vol.3, issue.3, pp.276-284, 2002.
DOI : 10.1002/1439-7641(20020315)3:3<276::AID-CPHC276>3.0.CO;2-A

P. Fromherz, O. Müller, and R. Weis, Neuron transistor: Electrical transfer function measured by the patch-clamp technique, Physical Review Letters, vol.71, issue.24, pp.71-4079, 1993.
DOI : 10.1103/PhysRevLett.71.4079

P. Fromherz and A. Stett, Silicon-Neuron Junction: Capacitive Stimulation of an Individual Neuron on a Silicon Chip, Physical Review Letters, vol.75, issue.8, pp.75-1670, 1995.
DOI : 10.1103/PhysRevLett.75.1670

F. Patolsky, B. Timko, G. Yu, Y. Fang, A. Greytak et al., Detection, Stimulation, and Inhibition of Neuronal Signals with High-Density Nanowire Transistor Arrays, Science, vol.313, issue.5790, pp.313-1100, 2006.
DOI : 10.1126/science.1128640

M. Jungblut, W. Knoll, C. Thielemann, and M. Pottek, Triangular neuronal networks on microelectrode arrays: an approach to improve the properties of low-density networks for extracellular recording, Biomedical Microdevices, vol.22, issue.46, pp.11-1269, 2009.
DOI : 10.1007/s10544-009-9346-0

M. R. Hynd, J. P. Frampton, N. Dowell-mesfin, J. N. Turner, and W. Shain, Directed cell growth on protein-functionalized hydrogel surfaces, Journal of Neuroscience Methods, vol.162, issue.1-2, pp.162-255, 2007.
DOI : 10.1016/j.jneumeth.2007.01.024
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729282

N. S. Baek, J. Lee, Y. H. Kim, B. J. Lee, G. H. Kim et al., Photopatterning of Cell-Adhesive-Modified Poly(ethyleneimine) for Guided Neuronal Growth, Langmuir, vol.27, issue.6, pp.2717-2722, 2011.
DOI : 10.1021/la103372v

J. Wang, L. Ren, L. Li, W. Liu, J. Zhou et al., Microfluidics: A new cosset for neurobiology, Lab Chip, vol.7, issue.5, pp.9-644, 2009.
DOI : 10.1039/B813495B

. Xu, Photopatterning of self-assembled poly(ethylene)glycol monolayer for neuronal network fabrication, Journal of Neuroscience Methods, vol.213, pp.196-203, 2013.

W. C. Chang and D. W. Sretavan, Novel High-Resolution Micropatterning for Neuron Culture Using Polylysine Adsorption on a Cell Repellant, Plasma-Polymerized Background, Langmuir, vol.24, issue.22, pp.13048-13057, 2008.
DOI : 10.1021/la8021479

. Temple-boyer, Development of pNH4-ISFET microsensors for water analysis, Microelectronics Journal, vol.37, pp.475-479, 2006.

F. Larramendy, F. Mathieu, S. Charlot, L. Nicu, and P. Temple-boyer, Parallel detection in liquid phase of N-channel MOSFET/ChemFET microdevices using saturation mode, Sensors and Actuators B: Chemical, vol.176, pp.176-379, 2013.
DOI : 10.1016/j.snb.2012.09.091
URL : https://hal.archives-ouvertes.fr/hal-01508106

F. Larramendy, L. Mazenq, P. Temple-boyer, and L. Nicu, Three-dimensional close microfluidic channels fabrication by stepper projection single step lithography: the diabolo effect, Lab on a chip, pp.12-387, 2012.

J. Secco-d-'aragona, Dislocation Etch for (100) Planes in Silicon, Journal of The Electrochemical Society, vol.119, issue.7, pp.948-952, 1972.
DOI : 10.1149/1.2404374

B. A. Barres, B. E. Silverstein, D. P. Corey, and L. L. Chun, Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning, Neuron, vol.1, issue.9, pp.1-791, 1988.
DOI : 10.1016/0896-6273(88)90127-4

M. Kyriakides, C. R. Mac-crhan, C. T. Slade, N. I. Syed, and W. Winlow, The morphology and electrophysiology of the neurones of the paired pedal ganglia of Lynaea stagnalis (L.), Comparative Biochemistry and Physiology Part A: Physiology, vol.93, issue.4, pp.861-876, 1989.
DOI : 10.1016/0300-9629(89)90513-6

R. L. Ridgway, N. I. Syed, K. Lukowiak, and A. G. Bulloch, Nerve growth factor (NGF) induces sprouting of specific neurons of the snail,Lymnaea stagnalis, Journal of Neurobiology, vol.1, issue.4, pp.22-377, 1991.
DOI : 10.1002/neu.480220406

A. A. Prinz and P. Fromherz, Electrical synapses by guided growth of cultured neurons from the snail Lymnaea stagnalis, Biological Cybernetics, vol.82, issue.4, pp.1-5, 2000.
DOI : 10.1007/PL00007969

M. Jenkner, B. Müller, and P. Fromherz, Interfacing a silicon chip to pairs of snail neurons connected by electrical synapses, Biological Cybernetics, vol.84, issue.4, pp.239-249, 2001.
DOI : 10.1007/s004220000218

A. Cohen, M. E. Spira, S. Yitshaik, G. Borghs, O. Schwartzglass et al., Depletion type floating gate p-channel MOS transistor for recording action potentials generated by cultured neurons, Biosensors and Bioelectronics, vol.19, issue.12, pp.19-1703, 2004.
DOI : 10.1016/j.bios.2004.01.021

F. Moccia, C. Di-cristo, W. Winlow, and A. D. Cosmo, GABAA- and AMPA-like receptors modulate the activity of an identified neuron within the central pattern generator of the pond snail Lymnaea stagnalis, Invertebrate Neuroscience, vol.94, issue.1, pp.9-29, 2009.
DOI : 10.1007/s10158-009-0086-x

F. Walther, P. Davydovskaya, S. Zürcher, M. Kaiser, H. Herberg et al., Stability of the hydrophilic behavior of oxygen plasma activated SU-8, Journal of Micromechanics and Microengineering, vol.17, issue.3, pp.17-524, 2007.
DOI : 10.1088/0960-1317/17/3/015

L. Qiana and W. M. Saltzman, Improving the expansion and neuronal differentiation of mesenchymal stem cells through culture surface modification, Biomaterials, vol.25, issue.7-8, pp.25-1331, 2004.
DOI : 10.1016/j.biomaterials.2003.08.013

B. Kolomiets, E. Dubus, M. Simonutti, S. Rosolen, J. A. Sahel et al., Late histological and functional changes in the P23H rat retina after photoreceptor loss, Neurobiology of Disease, vol.38, issue.1, pp.38-47, 2010.
DOI : 10.1016/j.nbd.2009.12.025

G. E. Spencer, N. I. Syed, and K. Lukowiak, Neural changes after operant conditioning of the aerial respiratory behaviour in Lymnae Stagnalis, The journal of neuroscience, vol.19, pp.1835-1843, 1999.

F. Larramendy-was-born-in-brive-la-gaillarde and F. , He joined the Laboratory for Analysis and Architecture of Systems (LAAS), National Center of Scientific Research (CNRS) Toulouse in 2009 as PhD Student. He was in charge of the development of microsystems to measure neuronal activities. After obtaining his D. Sc. Degree in 2013, he joined the EUJO-LIMMS project in the Microsystem Materials Laboratory, Microelectronic System Engineering from the Paul Sabatier University, and the Laboratory for Integrated Micro Mechatronic Systems (LIMMS), Tokyo, Japan. Currently, he is in charge of the development of microprobes for brain insertion for biomedical applications, 1986.

M. C. Blatché-was-born-in-toulouse and F. , She received the Licence degree in Biotechnologies from Nice-Sophia Antipolis University, Centre National de la Recherche Scientifique (CNRS) Toulouse in 2009, where she is in charge of the "Biology" technological platform and worked on the development of cell growth on microsystems, 1986.

F. Mathieu-was-born, He received the engineering degree in communication systems and electronics from the CNAM (Conservatoire National des Arts et Métiers) He joined the Laboratoire d'Analyse et d, LAAS), Centre National de la Recherche Scientifique (CNRS) where he is currently in charge of the development and design of very low signal detection systems applied to the micro(nano)electromechanical systems area and its complete electronic treatment and control for automation, 1972.

S. Picaud-was-born-in and . Paris, He received a PhD in Neurosciences from the University of Marseille in 1990 He was educated by leaders in the field of retinal physiology during doctoral and postdoctoral stays with Professor Wässle (Max-Planck Institute for Brain research, Francfurt, Germany) and Prpfessor Werblin (University of California He is currently leading the team " retinal information processing " at the Vision Institute in Paris created by Professor Sahel. After studying retinal physiology and pharmacology with applications in neuroprotection, the team has moved toward strategies for restoring vision in blind patients having lost their photoreceptors, These strategies involve retinal prostheses or optogenetic therapy, which requires expression of photosensitive pump or ionic channels in selected retinal neurones, 1961.

C. National-de-la-recherche and . Scientifique, LAAS-CNRS) in 1992 and received the PhD degree from the Institut National des Sciences Appliquées de Toulouse (France) in 1995. Since then, as a senior researcher, he has been working on the development of micro-and nanotechnologies