Antimicrobial resistance and virulence common mechanisms (ebook)

Etienne Giraud (1, 2) , Ivan Rychlik (3) , Axel Cloeckaert (2)

1 ToxAlim - ToxAlim
2 UMR ISP - Infectiologie et Santé Publique
3 Department of Immunology

Multiple relationships exist between antimicrobial resistance and bacterial virulence, and the spread of clones combining multiple antibiotic resistance and a high virulence level is an increasing problem. It was previously described how mutation-driven or horizontally acquired resistance mechanisms can also have effects on virulence. It was also reported that mobile genetic elements often carry both resistance determinants and virulence-modulating genes, which favors the co-selection of both traits. In the present volume, we present a collection of articles which document additional aspects of the interactions between antimicrobial resistance and virulence in bacteria, and describe their potential therapeutic consequences.

Mots clés: biofilms; fitness costs; co-évolution; antimicrobial resistance mechanisms; virulence

Domaines: Sciences du Vivant [q-bio]

Etienne Giraud, Ivan Rychlik, Axel Cloeckaert (Dir.). Antimicrobial resistance and virulence common mechanisms (ebook). Frontiers Media, 138 p., 2017, Frontiers in Microbiology, 9782889451814. ⟨10.3389/978-2-88945-181-4⟩. ⟨hal-01605380⟩