MODELLING OF UREA-ENFETS FOR HAEMODIALYSIS APPLICATIONS

Pierre Temple-Boyer (1) , Ahmed Benyahia (1) , William Sant (1) , Marie Laure L Pourciel-Gouzy (1) , Jérôme Launay (1) , Augustin Martinez (1)

1 LAAS-MICA - Équipe MICrosystèmes d'Analyse

The detection properties of enzymatic field effect transistors (EnFETs) based on pH-sensitive chemical field effect transistors (pH-ChemFETs) are modelled by taking into account the enzymatic reaction, the diffusion phenomena of the main chemical species in the electrolyte, the related acid/basic chemical reactions and the pH-ISFET potentiometric response. Thus, the pH distribution near the pH sensitive gate is characterized and the sensor detection properties have been studied as a function of the main analysis parameters. The modelling is developed for haemodialysis applications and more especially for the optimisation of urea-sensitive EnFETs. However, it is fully compatible with other EnFETs developments based on pH-ChemFET-metry.

Mots clés: haemodialysis; urea detection; EnFETs; Modelling

Domaines: Micro et nanotechnologies/Microélectronique

Pierre Temple-Boyer, Ahmed Benyahia, William Sant, Marie Laure L Pourciel-Gouzy, Jérôme Launay, et al.. MODELLING OF UREA-ENFETS FOR HAEMODIALYSIS APPLICATIONS. Sensors and Actuators B: Chemical, 2008, 131 (2), pp.525 - 532. ⟨10.1016/j.snb.2007.12.037⟩. ⟨hal-01687855⟩