The effect of gamma sterilization on pH-ISFETs behaviour for single-use bioreactors

Iryna Humenyuk (1) , Pierre Temple-Boyer (1) , Gérard Sarrabayrouse (1)

1 LAAS-MICA - Équipe MICrosystèmes d'Analyse

One of the key requirements biomedical and pharmaceutical sensors have to satisfy is their ability to withstand sterilization cycle. In this paper, the influence of gamma sterilization on the electrical and electrochemical characterizations of pH-ISFET sensors is examined before and after gamma irradiation. The ion-sensitive field effect transistor (ISFET) was intended for use in single-use bioreactor. It is shown that pH-ISFET is suitable for use in vitro analysis and more precisely for bioreactors.

Mots clés: pH-ISFET sensor; ReMOS; gamma-sterilization

Domaines: Micro et nanotechnologies/Microélectronique

Iryna Humenyuk, Pierre Temple-Boyer, Gérard Sarrabayrouse. The effect of gamma sterilization on pH-ISFETs behaviour for single-use bioreactors. Sensors and Actuators A: Physical , 2008, 147 (1), pp.165 - 168. ⟨10.1016/j.sna.2008.05.022⟩. ⟨hal-01687858⟩