MODELLING OF ENFETS FOR THE CREATININE DETECTION

Pierre Temple-Boyer 1 J. Le Gal 1 Marie Laure Pourciel-Gouzy 1 William Sant 1 A. Martinez 1
1 LAAS-MICA - Équipe MICrosystèmes d'Analyse
LAAS - Laboratoire d'analyse et d'architecture des systèmes
Abstract : Creatinine enzymatic field effect transistors (C-EnFETs) realised from a pH-sensitive field effect transistor (pH-ISFET) have been modelled by taking into account the enzymatic reaction, the diffusion phenomena of the main chemical species in the electrolyte, the related acid/basic chemical reactions in watery solution and the detection properties of the pH-ISFET sensitive gate. Thus, the concentrations of the main chemical species have been characterized near the sensitive gate, and the C-EnFET micro sensor detection properties have been studied according to the most influential parameters. A good fit has been shown between modelling and experimental results. The model has been developed for the optimization of creatinine-EnFETs in the field of haemodialysis, but is also fully compatible for other EnFETs based on pH-ISFET-metry.
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Pierre Temple-Boyer, J. Le Gal, Marie Laure Pourciel-Gouzy, William Sant, A. Martinez. MODELLING OF ENFETS FOR THE CREATININE DETECTION. Sensors and Actuators B: Chemical, Elsevier, 2006, 118 (1-2), pp.47 - 52. ⟨10.1016/j.snb.2006.04.011⟩. ⟨hal-01687860⟩

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