Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

Isabelle Ader (1) , Cécile Gstalder (1) , Pierre Bouquerel (1) , Muriel Golzio (2) , Guillaume Andrieu (3) , Santiago Zalvidea (4) , Sylvain Richard (4) , Roger Sabbadini (5) , Bernard Malavaud (6) , Olivier Cuvillier (1)

1 IPBS - Institut de pharmacologie et de biologie structurale
2 CPTP - Centre de Physiopathologie Toulouse Purpan
3 XLIM-SRF - Systèmes RF
4 PhyMedExp - Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046]
5 Lpath Inc.
6 Department of Urology, University Hospital,

Domaines: Sciences du Vivant [q-bio]

Isabelle Ader, Cécile Gstalder, Pierre Bouquerel, Muriel Golzio, Guillaume Andrieu, et al.. Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer. Oncotarget, 2015, 6 (15), ⟨10.18632/oncotarget.3144⟩. ⟨hal-01764907⟩