Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice

Hélène Tronchère (1) , Mathieu Cinato (1) , Andrei Timotin (1) , Laurie Guitou (1) , Camille Villedieu (2) , Hélène Thibault (2) , Delphine Baetz (2) , Bernard Payrastre (1) , Philippe Valet (1) , Angelo Parini (1) , Oksana Kunduzova (1) , Frédéric Boal (1)

1 I2MC - Institut des Maladies Métaboliques et Cardiovasculaires
2 CarMeN - Cardiovasculaire, métabolisme, diabétologie et nutrition

Domaines: Sciences du Vivant [q-bio]

Hélène Tronchère, Mathieu Cinato, Andrei Timotin, Laurie Guitou, Camille Villedieu, et al.. Inhibition of PIKfyve prevents myocardial apoptosis and hypertrophy through activation of SIRT3 in obese mice. EMBO Molecular Medicine, 2017, 9 (6), pp.770 - 785. ⟨10.15252/emmm.201607096⟩. ⟨hal-01827485⟩