Light emitting devices and integrated electrochemical sensors on lab-on-chip for toxicity bioassays based on algal physiology

Abstract : In the frame of water toxicity analysis, a portable, glass-based, lab-on-chip was developed, integrating three-electrode electrochemical microsensors and organic light-emitting diodes (OLED). The basic detection principle consists in monitoring electrochemically O2-related, algal metabolism in presence of herbicides. Thus, aiming on Diuron herbicide detection, a concentration-dependent inhibition effect on photosynthetic oxygen production rate was evidenced in the [0-1 M] range. Finally, OLED-based integrated system demonstrates higher detection characteristics than those using external white light source (sensitivity: 0.48 versus 0.26 nA/s/M) and is highly promising for further integration of optical and electrochemical sensors enabling double complementary detection.
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Aliki Tsopela, Adrian Laborde, Ludovic Salvagnac, Isabelle Séguy, Ricardo Izquierdo, et al.. Light emitting devices and integrated electrochemical sensors on lab-on-chip for toxicity bioassays based on algal physiology. 18th international conference on solid-state sensors, actuators and microsystems (TRANSDUCERS 2015), Jun 2015, Anchorage, AK, United States. 4p., ⟨10.1109/TRANSDUCERS.2015.7181251⟩. ⟨hal-01874764⟩

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