(+)-Cinchonine-decorated dendrimers as recoverable organocatalysts
Résumé
First- and fourth-generation phosphorus dendrimers decorated on their surface with (+)-cinchonine moieties for the use as organocatalysts have been prepared. The first-generation dendrite showed the highest activity and enantioselectivity in the α-amination of several β-dicarbonyl compounds. A positive dendritic effect was observed. Its recovery and reuse over 10 cycles was demonstrated without loss of activity. Preliminary studies of the scope of the reaction have been performed.