Platinum(ii)-phosphole complexes: synthesis and evaluation as enyne cycloisomerisation catalysts

Kévin Fourmy (1, 2) , Sonia Mallet-Ladeira (3, 1) , Odile Dechy-Cabaret (1, 4) , Maryse Gouygou (1, 4)

1 LCC - Laboratoire de chimie de coordination
2 UT3 - Université Toulouse III - Paul Sabatier
3 ICT - Institut de Chimie de Toulouse
4 Toulouse INP - Institut National Polytechnique (Toulouse)

A series of platinum(ii)-monophosphole complexes has been synthesized and used in enyne cycloisomerisations in order to study the effect of the ligand on the catalytic activity and selectivity. Reactions were performed on various N- or C-tethered 1,6-enynes and in the absence or in the presence of nucleophiles. For the most efficient cationic Pt(ii)-complexes, it was also evidenced that the counterion and/or the solvent could have an influence on both the efficiency and the selectivity in the competition between the 5-exo-dig and the 6-endo-dig processes.

Domaines: Chimie de coordination

Kévin Fourmy, Sonia Mallet-Ladeira, Odile Dechy-Cabaret, Maryse Gouygou. Platinum(ii)-phosphole complexes: synthesis and evaluation as enyne cycloisomerisation catalysts. Dalton Transactions, 2014, 43 (18), pp.6728-6734. ⟨10.1039/C3DT53588F⟩. ⟨hal-02007960⟩