Identification of altered brain metabolites associated with TNAP activity in a mouse model of hypophosphatasia using untargeted NMR-based metabolomics analysis

Thomas Cruz (1) , Marie Gleizes (2) , Stéphane Balayssac (1) , Etienne Mornet (3) , Grégory Marsal (2) , José Luis Millán (4) , Myriam Malet-Martino (1) , Lionel G Nowak (2) , Véronique Gilard (1) , Caroline Fonta (2)

1 SPCMIB - Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique
2 CERCO - Centre de recherche cerveau et cognition
3 CHV - Centre Hospitalier de Versailles André Mignot
4 Sanford Burnham Prebys Medical Discovery Institute

Domaines: Chimie

Thomas Cruz, Marie Gleizes, Stéphane Balayssac, Etienne Mornet, Grégory Marsal, et al.. Identification of altered brain metabolites associated with TNAP activity in a mouse model of hypophosphatasia using untargeted NMR-based metabolomics analysis. Journal of Neurochemistry, 2017, 140 (6), pp.919-940. ⟨10.1111/jnc.13950⟩. ⟨hal-02060254⟩