Recent developments in miniaturized optical systems for continuous fluorescence detection in liquid flows

Daniel Măriuța (1) , Lucien Baldas (1) , Jürgen Brander (2) , Katja Haas-Santo , Stéphane Le Calvé (3) , Stéphane Colin (1) , Pascale Magaud (1) , Christine Barrot-Lattes (1)

1 ICA - Institut Clément Ader
2 INT - Institute of Nanotechnology [Karlsruhe]
3 ICPEES - Institut de chimie et procédés pour l'énergie, l'environnement et la santé

Miniaturization of continuous fluorescence detection is a challenging task due to the multiple and sensitive parameters intervening in the process. By analyzing fluorescence sensing architectures proposed during the last two years, this work has the goal to identify some trends in the process of fluorescence miniaturization for in-time liquid detection. A lack of postulated strategies regarding the miniaturization process was observed and this review tries to answer partially to this need. The identified integration strategies excel in fulfilling partially the desired functions of a fully autonomous miniaturized detector and further research is needed in order to develop sensing micro-system being capable to step outside of the lab world.

Mots clés: integration strategies; commercialization; miniaturization; Fluorescence; in-time detection; high sensitivity

Domaines: Mécanique des fluides [physics.class-ph]

Daniel Măriuța, Lucien Baldas, Jürgen Brander, Katja Haas-Santo, Stéphane Le Calvé, et al.. Recent developments in miniaturized optical systems for continuous fluorescence detection in liquid flows. 5th European Conference on Microfluidics (μFlu18) and 3rd European Conference on Non-Equilibrium Gas Flows (NEGF18), Feb 2018, Strasbourg, France. pp.391-394. ⟨hal-02062609⟩