Manganese-Catalyzed Transfer Hydrogenation of Aldimines

D. Wei (1) , Antoine Bruneau-Voisine (1) , M. Dubois (2) , Stéphanie Bastin (2) , Jean-Baptiste Sortais (2)

1 ISCR - Institut des Sciences Chimiques de Rennes
2 LCC - Laboratoire de chimie de coordination

The reduction of imines to amines via transfer hydrogenation was achieved promoted by phosphine‐free manganese(I) catalyst. Using isopropanol as reductant, in the presence of tBuOK (4 mol %) and manganese complex [Mn(CO)3Br(κ2N,N‐PyCH2NH2)] (2 mol %), a large variety of aldimines (30 examples) were typically reduced in 3 hours at 80 °C with good to excellent yield.

Mots clés: imines; manganese; reduction; amines; transfer hydrogenation

Domaines: Chimie

D. Wei, Antoine Bruneau-Voisine, M. Dubois, Stéphanie Bastin, Jean-Baptiste Sortais. Manganese-Catalyzed Transfer Hydrogenation of Aldimines. ChemCatChem, 2019, 11 (21), pp.5256-5259. ⟨10.1002/cctc.201900314⟩. ⟨hal-02122163⟩