Transmission of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a nephrology-transplant intensive care unit with potential link to the environment

Veronica Ambrogi (1) , Laurent Cavalié (2, 3) , Benoit Mantion (2) , Olivier Cointault (2) , Damien Dubois (2, 3) , Marie-Françoise Prère (4, 2) , Nicole Levitzki (1) , Nassim Kamar (2, 3, 5) , Sandra Malavaud (1)

1 Équipe opérationnelle d’hygiène hospitalière
2 CHU Toulouse - Centre Hospitalier Universitaire de Toulouse
3 INSERM - Institut National de la Santé et de la Recherche Médicale
4 LMGM - Laboratoire de microbiologie et génétique moléculaires - UMR5100
5 UT3 - Université Toulouse III - Paul Sabatier

Pseudomonas aeruginosa has been recovered in hospitals from many different sources including sinks and taps. Because P. aeruginosa is one of the main agents of nosocomial infections and increasingly resistant to antibiotics, environmental reservoirs in hospital settings are of great concern. We report here on a cluster of five cases of infection by P. aeruginosa expressing VIM carbapenemases (VIM-PA) in a nephrology intensive care unit. Our investigation pointed to transmission of VIM-PA via hands related to a contaminated tap. VIM-PA may be cross-transmitted to other patients if an environmental reservoir exists. Sinks and taps should be well designed and thoroughly cleaned and disinfected, and use of alcohol hand rub should be promoted. (C) 2015 The Healthcare Infection Society. Published by Elsevier Ltd.

Mots clés: Intensive care unit; Pseudomonas aeruginosa; VIM carbapenemase

Mots clés: Environmental source

Domaines: Sciences du Vivant [q-bio]

Veronica Ambrogi, Laurent Cavalié, Benoit Mantion, Olivier Cointault, Damien Dubois, et al.. Transmission of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a nephrology-transplant intensive care unit with potential link to the environment. Journal of Hospital Infection, 2016, 92 (1), pp.27-29. ⟨10.1016/j.jhin.2015.09.007⟩. ⟨hal-02635847⟩