Low generation PEGylated phosphorus-containing dendrons with phosphonate anchors

Clément Barrière (1) , Virginie Latour (1) , Pierre Fau (1) , Anne-Marie Caminade (1) , Cédric-Olivier Turrin (1)

1 LCC - Laboratoire de chimie de coordination

We present a simple strategy to obtain non-symmetrical polyethylene glycols equipped with telechelic phosphorus-containing dendrimeric moieties having adhesive phosphonate surface functions. The dendronized PEG tails were characterized by means of multi-nucleus NMR. The grafting abilities of model symmetrical PEG compounds equipped with telechelic amino-bis(methylene-dimethylphosphonates) and amino-bis(methylenephosphonic acids) were rapidly screened on plasma treated silicon wafers and activated silica.

Mots clés: Dendrimer; Phosphonate; PEG

Domaines: Chimie de coordination

Clément Barrière, Virginie Latour, Pierre Fau, Anne-Marie Caminade, Cédric-Olivier Turrin. Low generation PEGylated phosphorus-containing dendrons with phosphonate anchors. Tetrahedron Letters, 2012, 53 (15), pp.1908-1911. ⟨10.1016/j.tetlet.2012.01.138⟩. ⟨hal-02908969⟩