Dendritic phosphoramidite ligands for Rh-catalyzed [2+2+2] cycloaddition reactions: unprecedented enhancement of enantiodiscrimination

Lídia Garcia (1, 2) , Anna Roglans (1) , Regis Laurent (2) , Jean Pierre Majoral (2) , Anna Pla-Quintana (1) , Anne-Marie Caminade (2)

1 UdG - Universitat de Girona
2 LCC - Laboratoire de chimie de coordination

Phosphorus dendrimers containing terminal phosphoramidite ligands have been found to be highly effective and recoverable catalysts for the rhodium(I) catalyzed [2+2+2] cycloaddition reactions. A strong positive dendritic effect is observed both in the activity and enantiodiscrimination leading to axially chiral biaryl compounds.

Domaines: Chimie de coordination

Lídia Garcia, Anna Roglans, Regis Laurent, Jean Pierre Majoral, Anna Pla-Quintana, et al.. Dendritic phosphoramidite ligands for Rh-catalyzed [2+2+2] cycloaddition reactions: unprecedented enhancement of enantiodiscrimination. Chemical Communications, 2012, 48 (74), pp.9248. ⟨10.1039/c2cc32992a⟩. ⟨hal-02909815⟩