Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload–Induced Cardiac Fibrosis

Chenghao Liu (1) , Seok Ting Lim (1) , Melissa Hui Yen Teo (1) , Michelle Si Ying Tan (1) , Madhura Dattatraya Kulkarni (1) , Beiying Qiu (2) , Amy Li (3) , Sean Lal (3) , Cristobal dos Remedios (3) , Nguan Soon Tan (1, 2, 4) , Walter Wahli (5, 1, 6) , Michael Alan Ferenczi (1) , Weihua Song (1) , Wanjin Hong (2, 7) , Xiaomeng Wang (1, 2, 8, 9)

1 Nanyang Technological University [Singapour]
2 A*STAR - Agency for science, technology and research [Singapore]
3 The University of Sydney
4 KKH - KK Women’s and Children’s Hospital
5 ToxAlim - ToxAlim
6 UNIL - Université de Lausanne = University of Lausanne
7 ‎ National Heart Centre Singapore
8 Institute of Ophthalmology [London]
9 SERI - Singapore Eye Research Institute [Singapore]

Domaines: Sciences du Vivant [q-bio]; Médecine humaine et pathologie

Chenghao Liu, Seok Ting Lim, Melissa Hui Yen Teo, Michelle Si Ying Tan, Madhura Dattatraya Kulkarni, et al.. Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload–Induced Cardiac Fibrosis. Circulation. Heart failure, 2019, 12 (12), ⟨10.1161/CIRCHEARTFAILURE.119.005962⟩. ⟨hal-02963615⟩