Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study

S. Incerti (1) , M. Psaltaki (2) , P. Gillet (1) , P. Barberet (1) , M. Bardiès (3) , M.A. Bernal (4) , M.-C. Bordage (3) , V. Breton (5) , M. Davidkova (6) , E. Delage (5) , Z. El Bitar (7) , Z. Francis (8) , S. Guatelli (9) , A. Ivanchenko (10) , V. Ivanchenko (10, 11) , M. Karamitros (1, 12) , S.B. Lee (13) , L. Maigne (5) , S. Meylan (14) , K. Murakami (15) , P. Nieminen (16) , H. Payno (5) , Y. Perrot (5) , I. Petrovic (17) , Q.T. Pham (5) , A. Ristic-Fira (17) , G. Santin (16) , T. Sasaki (15) , H. Seznec (1) , J.I. Shin (13) , V. Stepan (6) , H.N. Tran (18) , C. Villagrasa (14)

1 CENBG - Centre d'Etudes Nucléaires de Bordeaux Gradignan
2 NTUA - National Technical University of Athens [Athens]
3 IUCT Oncopole - UMR 1037 - Institut Universitaire du Cancer de Toulouse - Oncopole
4 INSTITUTO DE FISICA "GLEB WATAGHIN" - Instituto de Fisica "Gleb Wataghin"
5 LPC - Laboratoire de Physique Corpusculaire - Clermont-Ferrand
6 Department of Radiation Dosimetry
7 IPHC - Institut Pluridisciplinaire Hubert Curien
8 Department of Physics, Faculty of Sciences
9 Centre for Medical Radiation Physics
10 G4AI - Geant4 Associates International
11 Ecoanalytica
12 INCIA - Institut de Neurosciences cognitives et intégratives d'Aquitaine
13 Proton Therapy Center
14 IRSN - Institut de Radioprotection et de Sûreté Nucléaire
15 High energy accelerator research organization - KEK
16 ESTEC - European Space Research and Technology Centre
17 Vinča Institute of Nuclear Sciences
18 Ton Duc Thang University [Hô-Chi-Minh-City]

An accurate modeling of radial energy deposition around ion tracks is a key requirement of radiation transport software used for simulations in radiobiology at the sub-cellular scale. The work presented in this paper is part of the on-going benchmarking of the "Geant4-DNA" physics processes and models, which are available in the Geant4 Monte Carlo simulation toolkit for the low energy transport of particles in liquid water. We present for the first time radial dose distributions of incident ion tracks simulated with "Geant4-DNA". Simulation results are compared to other results available in the literature, obtained from analytical calculations, step-by-step Monte Carlo simulations and measurements. They show a reasonable agreement with reference data. © 2014 Elsevier B.V. All rights reserved.

Mots clés: DNA; Monte Carlo methods; Analytical calculation; Comparative studies; Dose; Energy depositions; Geant4 dnas; Liquid water; Monte- carlo simulations; Radiation transport; Liquids

Domaines: Physique [physics]

S. Incerti, M. Psaltaki, P. Gillet, P. Barberet, M. Bardiès, et al.. Simulating radial dose of ion tracks in liquid water simulated with Geant4-DNA: A comparative study. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 2014, 333, pp.92-98. ⟨10.1016/j.nimb.2014.04.025⟩. ⟨hal-03118554⟩