Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action.

Dominique Langin (1, 2, 3)

1 I2MR - Institut de médecine moléculaire de Rangueil
2 Franco-Czech Laboratory for Clinical Research on Obesity
3 Laboratoire de Biochimie [CHU Toulouse]

Lactate is produced from glucose by adipose tissue. In this issue of Cell Metabolism, Ahmed et al. (2010) show that the metabolite is involved in the antilipolytic effect of insulin, providing a new link between fat and carbohydrate metabolism.

Domaines: Biochimie, Biologie Moléculaire

Dominique Langin. Adipose tissue lipolysis revisited (again!): lactate involvement in insulin antilipolytic action.. Cell Metab, 2010, 11 (4), pp.242-3. ⟨10.1016/j.cmet.2010.03.003⟩. ⟨inserm-00613669⟩