Acetylcholinesterase activity in Clytia hemisphaerica (Cnidaria)

Elsa E. Denker (1) , Arnaud Chatonnet (2) , Nicolas N. Rabet (1)

1 Evolution et Développement
2 DCC - Différenciation Cellulaire et Croissance

Cholinesterase activity is known in representatives of all living organisms phyla but the origin of the cholinergic system as known in bilaterian animals is still undeciphered. In particular the implication of cholinesterases in the nervous system of non-bilaterian Metazoa is not well known, We thus chose to investigate this activity in the Clytia hemisphaerica (Cnidaria) medusa. In toto histochemical staining revealed an acetylcholinesterase activity in the tentacle bulbs but not in the nervous system. Sequences homologous to acetylcholinesterase were searched within Clytia ESTs and compared to other sequences found in public databases.

Keywords: Cnidarian; Clytia hemisphaerica; Acetylcholine; Acetylcholinesterase; Neuroligin; nonneuronal acetylcholine; expression; humans; hydra

Domains: Agricultural sciences; Animal biology; Development Biology

Elsa E. Denker, Arnaud Chatonnet, Nicolas N. Rabet. Acetylcholinesterase activity in Clytia hemisphaerica (Cnidaria). Chemico-Biological Interactions, 2008, 175 (1-3), pp.125-128. ⟨10.1016/j.cbi.2008.03.004⟩. ⟨hal-01004092⟩