Straightforward Access to alpha-Methylamines through Cross-Metathesis

Florent Poulhès (1) , Remy Sylvain (2) , Patricia Perfetti , Michèle P. Bertrand (1) , Gérard Gil (3) , Stéphane Gastaldi (1)

1 ICR - Institut de Chimie Radicalaire
2 LCC - Laboratoire de chimie de coordination
3 ISM2 - Institut des Sciences Moléculaires de Marseille

A two-step procedure involving cross-metathesis and reductive amination enables easy access to alpha-methylamines and alpha,alpha'-dimethyldiamines from a wide variety of terminal olefins.

Domaines: Chimie

Florent Poulhès, Remy Sylvain, Patricia Perfetti, Michèle P. Bertrand, Gérard Gil, et al.. Straightforward Access to alpha-Methylamines through Cross-Metathesis. Synthesis: Journal of Synthetic Organic Chemistry, 2010, 8, pp.1334--1338. ⟨10.1055/s-0029-1218672⟩. ⟨hal-01460251⟩